Young Jeezy isn't among those nay-sayers.
"Everybody got their lane. This industry is a highway and everybody got their lane and me and Jay ain't in the same lane," Young Jeezy told AllHipHop.com. "I don't feel what he's doing is interfering with what I'm doing. We do two different types of music for two different types of movements. Real n***as are glad he's back."
Jay-Z's Kingdom Come sold nearly 700,000 its first week in stores.
LL Cool J, the first artist signed to Def Jam, has been vocal about his disenchantment, to the extent that he would depart his only recording home.
"How am I gonna re-sign with competition? I'm not an idiot," LL Cool J told MTV. "I can't depend on that man (Jay-Z) to promote my record while he's somewhere writing rhymes."
Jay-Z hasn't responded publicly to LL's most recent statement, but Jeezy didn't feel Jay-Z's comeback as a recording artist would interrupt his career.
"He's back for a lot of different reasons," Jeezy said. "As a hustler, I'm not worried about him being back. This is what I do. For a n***a that ain't on his s**t, he might want to be worried."
Jeezy's own album The Inspiration: Thug Motivation 102, is set to be released on December 12 and the rapper maintains that he's been extremely proactive in all facets of production.
"As far as my project, I'm hands on with everything. Ain't nothing about to happen with my project that I ain't got to do with," he said. "I got good relationships [with Def Jam].